Test Code UPH24 pH, 24 Hour, Urine
Performing Laboratory

Specimen Type
UrineNecessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Supplies:
Diazolidinyl Urea (Germall), 5.0 mL (T822)
Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube or a clean, plastic aliquot container
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours
2. Add 5 mL of diazolidinyl urea as preservative at start of collection or refrigerate specimen during and after collection.
3. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH >8 indicate bacterial contamination, and testing will be cancelled. Do not attempt to adjust pH as it will adversely affect results.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 7 days |
Frozen | 7 days |
Reference Values
4.5-8.0
CPT Code Information
83986
Clinical Information
Urine pH is a measure of the acidity/alkalinity of urine and, by itself, usually provides little useful information. Under normal conditions its value is influenced by the type of diet. Some diets (eg, diets rich in meat) have more acid content than others (eg, vegetarian diets).
Changes in urine pH may reflect systemic acid-base disorders. For example, the normal response during metabolic acidosis is a lowering of the urine pH to less than 5. If the pH is greater than 5, then a defect in urine acidification should be considered. A urine pH of greater than 8 is suggestive of infection by a urea-splitting organism such as Proteus mirabilis.
Therapeutic interventions to either alkalinize or acidify the urine are necessary for some diseases. For example, some crystals have a propensity to form in alkaline urine, while others form in relative acidic urine, and changing the pH may reduce stone formation.
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Method Name
pH Meter
Day(s) Performed
Monday through Sunday