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Test Code STLP St. Louis Encephalitis Antibody, IgG and IgM, Serum

Method Name

Immunofluorescence Assay (IFA)

Specimen Type

Serum


Ordering Guidance


This assay detects only St. Louis virus. For a complete arbovirus panel, order ARBOP / Arbovirus Antibody Panel, IgG and IgM, Serum.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Clinical Information

The onset of St. Louis encephalitis is characterized by generalized malaise, fever, chilliness, headache, drowsiness, nausea, and sore throat or cough followed in 1 to 4 days by the meningeal and neurologic signs. The severity of illness increases with advancing age; persons over 60 years have the highest frequency of encephalitis. Symptoms of irritability, sleeplessness, depression, memory loss, and headaches can last up to 3 years. Areas of outbreaks since 1933 have involved the western United States, Texas, the Ohio-Mississippi Valley, and Florida. The vector of transmission is the mosquito. Peak incidence of St. Louis encephalitis is associated with summer and early autumn.

Reference Values

IgG: <1:10

IgM: <1:10

Reference values apply to all ages.

Day(s) Performed

Monday through Friday (May through October)

Monday, Wednesday, Friday (November through April)

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86653 x 2

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.

Testing Algorithm

For more information see Mosquito-borne Disease Laboratory Testing.