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Test Code SPNC Streptococcus pneumoniae Antigen, Spinal Fluid

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

CSF


Additional Testing Requirements


According to the College of American Pathologists (CAP Immunology Checklist, IMM.41830), cerebrospinal fluid (CSF) samples collected to make an initial diagnosis and submitted for detection of Streptococcus pneumoniae antigen testing should also be submitted for routine bacterial culture. Mayo Clinic Laboratories recommends that CSF bacterial cultures be performed at the originating site.



Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 1 mL

Collection Instructions: Submit specimen collected in vial 2, if possible. If not possible, note the vial from which the aliquot was obtained.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

Negative

 

Reference values apply to all ages.

Day(s) Performed

Monday through Sunday

CPT Code Information

87899

Clinical Information

Streptococcus pneumoniae is the most frequently encountered bacterial agent of community-acquired pneumonia and can also be an agent of bacterial meningitis. Because of the significant morbidity and mortality associated with pneumococcal pneumonia, septicemia, and meningitis, it is important to have diagnostic test methods available that can provide a rapid diagnosis. In instances where empirical antibiotics are being considered prior to culture confirmation, antigen testing may be useful.

Report Available

Same day/1 day

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Method Name

Immunochromatographic Membrane Assay

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.