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Test Code RCHLU Chloride, Random, Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Container/Tube: Plastic, 5-mL tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  7 days

Reference Values

No established reference values

Random urine chloride may be interpreted in conjunction with serum chloride, using both values to calculate fractional excretion of chloride.

 

The calculation for fractional excretion (FE) of chloride (Cl) is

FE(Cl) =(Cl [urine] x Creat [serum])/(Cl [serum] x Creat [urine]) x100

CPT Code Information

82436

Clinical Information

Chloride is the major extracellular anion. Its precise function in the body is not well understood; however, it is involved in maintaining osmotic pressure, proper body hydration, and electric neutrality. In the absence of acid-base disturbances, chloride concentrations in plasma will generally follow those of sodium.

 

Since urine is the primary mode of elimination of ingested chloride, urinary chloride excretion during steady state conditions will reflect ingested chloride, which predominantly is in the form of sodium chloride. However, under certain clinical conditions, the renal excretion of chloride may not reflect intake. For instance, during states of extracellular volume depletion, urine chloride (and sodium) excretion is reduced.

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Potentiometric, Indirect Ion-Selective Electrode (ISE)

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days