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Test Code PTU Protein, Total, 24 Hour, Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: 24-hour graduated urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 5 mL tube or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours. Specimens should be collected before fluorescein is given or not collected until at least 24 hour later.

2. No preservative.

3. Invert well before taking 4-mL aliquot.

4. Do not over fill aliquot tube 4 mL at most.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  24 hours

Reference Values

≥18 years: <229 mg/24 hours

Reference values have not been established for patients <18 years of age.

Reference value applies to 24-hour collection.

CPT Code Information

84156

Clinical Information

Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands.

 

Increased amounts of protein in the urine may be due to:

-Glomerular proteinuria: caused by defects in permselectivity of the glomerular filtration barrier to plasma proteins (eg, glomerulonephritis or nephrotic syndrome)

-Tubular proteinuria: caused by incomplete tubular reabsorption of proteins (eg, interstitial nephritis)

-Overflow proteinuria: caused by increased plasma concentration of proteins (eg, multiple myeloma, myoglobinuria)

-Urinary tract inflammation or tumor

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Turbidimetry

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

No

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

No

Boric Acid

OK

Diazolidinyl Urea

OK

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

OK

Toluene

No

 

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day