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HelpTest Code OLIGC Oligoclonal Banding, Spinal Fluid
Specimen Required
Only orderable as part of a profile. For more information, see:
-OLIG / Oligoclonal Banding, Serum and Spinal Fluid
-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid
Specimen Type: Spinal fluid
Container/Tube: Sterile vial
Specimen Volume: 0.5 mL
Collection Instructions: Label specimen as spinal fluid.
Method Name
Only orderable as part of a profile. For more information, see:
-OLIG / Oligoclonal Banding, Serum and Spinal Fluid
-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid
Isoelectric Focusing (IEF) with IgG Immunoblot Detection
Specimen Type
CSFSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Refrigerated (preferred) | 14 days |
| Ambient | 14 days | |
| Frozen | 14 days |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Clinical Information
The diagnosis of multiple sclerosis (MS) is dependent on clinical, radiological, and laboratory findings. The detection of increased intrathecal immunoglobulin (Ig) synthesis is the basis for current diagnostic laboratory tests for MS. These tests include the cerebrospinal fluid (CSF) IgG index and CSF oligoclonal band (OCB) detection. Abnormal CSF IgG indexes and OCB patterns have been reported in 70% to 80% of MS patients.
Increased intrathecal Ig synthesis may occur in other inflammatory CSF diseases and, therefore, this assay is not specific for MS.
Reference Values
Only orderable as part of a profile. For more information, see:
-OLIG / Oligoclonal Banding, Serum and Spinal Fluid
-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid
Cerebrospinal fluid Oligoclonal Bands Interpretation: <2 bands
Day(s) Performed
Monday through Friday
Report Available
4 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83916