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HelpTest Code KI67P Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated
Shipping Instructions
Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.
Necessary Information
1. Pathologist's name, address, and phone number are required.
2. Include accompanying pathology report stating the final diagnosis.
Specimen Required
Supplies: Pathology Packaging Kit (T554)
Specimen Type:
Preferred: Formalin-fixed, paraffin-embedded tissue block containing carcinoid/atypical carcinoid tumor of the lung including metastases.
Acceptable: 2 Unstained sections containing carcinoid/atypical carcinoid tumor of the lung including metastases on charged slides cut at 4 microns <1 month ago. Tissue on the slides should have been fixed in 10% neutral buffered formalin.
Container/Tube: Pathology Packaging Kit
Collection Instructions: Submit formalin-fixed, paraffin-embedded tissue block.
Additional Information: Paraffin block will be returned with the final report.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| KIPM | Ki67 Pulmonary IHC Manual | No | No |
Testing Algorithm
Cases that are unable to be scanned for automated analysis will be changed to KIPM / Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Manual.
Method Name
Immunohistochemistry, Automated Quantitation, Hot-Spot Technique
Specimen Type
SpecialSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Special | Ambient (preferred) | |
| Refrigerated | ||
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
Ki-67(MIB-1 clone) is a monoclonal antibody that reacts with cells undergoing DNA synthesis by binding to the Ki-67 antigen, a marker known to be expressed only in proliferating cells. By measuring the amount of tumor cells expressing Ki-67, an estimate of DNA synthesis can be determined. Studies suggest that Ki-67(MIB-1) analysis of paraffin-embedded tissue specimens may provide useful prognostic information in various tumor types.
Reference Values
Varies by tumor type; values reported from 0% to 100%
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
88361
Forms
If not ordering electronically, complete, print, and send a Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763) with the specimen.