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HelpTest Code HGUOE Mercury Occupational Exposure, Random, Urine
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen.
2. See Metals Analysis Specimen Collection and Transport for complete instructions.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HGOU | Mercury Occupational Exposure | No | Yes |
| CRETR | Creatinine, Random, U | No | Yes |
Method Name
HGOU: Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)
CRETR: Enzymatic Colorimetric Assay
Specimen Type
UrineSpecimen Minimum Volume
1.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 7 days |
| Frozen | 7 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
The correlation between the levels of mercury (Hg) excretion in the urine and the clinical symptoms is considered poor.
Previous thought indicated urine as a more appropriate marker of inorganic mercury because organic mercury represented only a small fraction of urinary mercury. Based on possible demethylation of methylmercury within the body, urine may represent a mixture of dietary methylmercury and inorganic mercury. Seafood consumption can contribute to urinary mercury levels (up to 30%),(1) which is consistent with the suggestion that due to demethylation processes in the human body, a certain proportion of urinary mercury can originate from dietary consumption of fish/seafood.(2)
For more information see HG / Mercury, Blood.
Reference Values
MERCURY/CREATININE:
Biological Exposure Index (BEI): <35 mcg/g creatinine prior to shift
CREATININE:
≥18 years: 16-326 mg/dL
Reference values have not been established for patients who are younger than 18 years of age.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83825
82570
Day(s) Performed
Monday through Friday