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Test Code HBGCD Hepatitis B Surface Antigen for Cadaveric or Hemolyzed Specimens, Serum

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
BNTCD HBsAg Confirm Cadav/Hemol, S No No

Testing Algorithm

All reactive results are confirmed by a neutralization procedure at an additional charge.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Additional Testing Requirements


Testing for acute hepatitis B virus (HBV) infection should also include HBIM / Hepatitis B Core IgM Antibody, Serum as during the acute HBV infection "window period," HB surface (HBs) antigen and HBs antibody may not be detected.



Necessary Information


Date of collection is required.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.


Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 30 days
  Ambient  7 days
  Refrigerated  7 days

Reference Values

Negative

Day(s) Performed

Monday, Thursday

CPT Code Information

87340

87341 (if appropriate)

Clinical Information

Hepatitis B virus (HBV) is endemic throughout the world. The infection is spread primarily through percutaneous contact with infected blood products (eg, blood transfusion, sharing of needles by intravenous drug users). The virus is found in various human body fluids, and it is known to be spread through oral and genital contact. HBV can be transmitted from mother to child during delivery through contact with blood and vaginal secretions; it is not commonly transmitted transplacentally.

 

Hepatitis B surface antigen (HBsAg) is the first serologic marker appearing in the serum at 6 to 16 weeks following HBV infection. In acute infection, HBsAg usually disappears in 1 to 2 months after the onset of symptoms. Persistence of HBsAg for greater than 6 months indicates development of either a chronic carrier or chronic HBV infection.

Report Available

1 to 7 days

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus Reject

Method Name

Enzyme Immunoassay (EIA)

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.