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Test Code CTU Creatinine, 24 Hour, Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: 24-hour graduated urine container with no metal cap or glued insert

Submission Container/Tube: Plastic tube or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen within 4 hours of completion of 24-hour collection.

Additional Information:

1. This test does not require the use of a chemical preservative; if a chemical preservative is used, it must be added to the specimen within 4 hours of completion of 24-hour collection.

2. See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 30 days
  Frozen  30 days
  Ambient  14 days

Reference Values

Reference values mg per 24 hours:

Males ≥18 years: 930-2955 mg/24 hours

Females ≥18 years: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are less than 18 years of age.

 

For SI unit Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html

CPT Code Information

82570

Clinical Information

Creatinine is formed from the metabolism of creatine and phosphocreatine, both of which are principally found in muscle. Thus the amount of creatinine produced is, in large part, dependent upon the individual's muscle mass and tends not to fluctuate much from day-to-day.

 

Creatinine is not protein bound and is freely filtered by glomeruli. All of the filtered creatinine is excreted in the urine. Renal tubular secretion of creatinine also contributes to a small proportion of excreted creatinine. Although most excreted creatinine is derived from an individual's muscle, dietary protein intake, particularly of cooked meat, can contribute to urinary creatinine levels.

 

The renal clearance of creatinine provides an estimate of glomerular filtration rate.

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Enzymatic Colorimetric Assay

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

OK

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

OK

Boric Acid

OK

Diazolidinyl Urea

OK

6M Hydrochloric Acid

OK

6M Nitric Acid

No

Sodium Carbonate

OK

Thymol

OK

Toluene

No

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Day(s) Performed

Monday through Sunday

Report Available

1 to 2 days