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Test Code BMIPB Borrelia miyamotoi Detection, PCR, Blood


Ordering Guidance


This assay does not detect the Borrelia species that cause Lyme disease. If Lyme disease is suspected, order SLYME / Lyme Antibody Modified 2-Tier with Reflex, Serum.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 1 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Testing Algorithm

For more information see Acute Tick-Borne Disease Testing Algorithm.

Method Name

Real-Time Polymerase Chain Reaction (PCR)

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated 7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Clinical Information

Borrelia miyamotoi is a spirochetal bacterium, closely related to the Borrelia species that causes tick-borne relapsing fever (TBRF), and it is more distantly related to the Borrelia species that cause Lyme disease. This organism causes a febrile illness like TBRF, with body and join pain, fatigue, and, rarely, rash. B miyamotoi has been detected in Ixodes scapularis and Ixodes pacificus ticks. These ticks are also the vectors for Lyme disease, anaplasmosis, and babesiosis.

 

The preferred method for detecting B miyamotoi is real-time polymerase chain reaction. Less sensitive and specific methods for detecting B miyamotoi and agents of TBRF include serologic testing and identification of spirochetes in peripheral blood films or spinal fluid preparations. This assay does not detect the Borrelia species that cause Lyme disease.

Reference Values

Negative

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

87478

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.